Treatment and Therapy

THE USAGE OF HERBAL MEDICINE IN DISEASE TREATMENT AND THERAPY

Introduction

Description of Herb

Aloe Vera is a medicinal herb that mostly grows in hot and dry climatic conditions. It is typically used to heal wound conditions of the skin and helps in improving baldness. On the other hand, the medicinal property of Aloe Vera helps in preventing oral fibrosis, burn and radiations in the mouth and inflammatory bowel conditions among people[1].

The taxonomic classification of Aloe Vera is discussed below

Domain: Eukaryota

Kingdom: Plantae

Phylum: Spermatophyta

Subphylum: Angiospermae

Class: Monocotyledonae

Order: Liliales

Family: Aloaceae

Genus: Aloe

Species: Aloe vera[2]

History

Aloe Verahas been used as a medicinal herb for the last 5000 years. Due to the anti-inflammatory and antioxidant properties of Aloe Vera, it has been called “the plant of immortality” at the time of pharaohs in Egypt. Arabic people of the Middle East area in ancient times used this herb for its medicinal value. In the time of Greco Roman era, physicians like Aristotle, Hippocrates and many others recommended Aloe Vera for preventing wounds, skincare treatment, genital ulcers alleviation and hair care treatments. It has been reported that the great Alexander concurred with Aloe Vera for the treatment of his soldier with the advice of Aristotle[3].

Background Information

Aloe Vera helps in preventing hepatitis, diabetes, and obesity-related issues among people. However, the antioxidant properties of Aloe Vera reduce the toxicity level of the body and help in avoiding cancer diseases. It is effective in dental plaque and constipation treatment. It also has anti-bacterial properties that are useful for the treatment of skin rashes, canker sores, wrinkles in the skin[4].

Medicinal properties

Usages

Aloe Vera has the following medicinal properties that have extensive usage in daily life. Those are discussed below

Antimicrobial property

Aloe vera helps in clearing skin rashes, acne, pimples. It improves the digestive system and promotes healthy life. On the other hand, it helps in reducing soreness in the mouth and oral infections[5].

Anti-inflammatory property

It has cooling, moisturizing, and soothing properties to reduce the burning sensation in the skin and make it healthier. Anti-inflammatory property of Aloe vera helps in reducing oral fibrosis disorders. It also helps in curing dangerous condition of inflammatory bowel disorders.

Antioxidant property

Aloe vera reduces the toxicity of the health and inhibits bacterial infection among health. It helps in reducing body weight and antioxidant property reduces cancer-causing reasons among people. All those properties of Aloe vera help in managing a healthier lifestyle among people[6].

[1]Nccih (2022)

[2]Cabi (2022)

[3]Atalayabio (2022)

[4]Azarfam et al. (2020)

[5]Liu et al. (2019)

[6]Sharma& Sharma (2019)

Figure 1: Medicinal properties of Aloe Vera

(Source: Sharma & Sharma 2019)

Active compounds

Aloe Vera has 75 active compounds that help in managing a huge number of medicinal properties among it. It has Vitamin A with beta carotene, Vitamin C, E, folic acid, and choline that provide antioxidant properties among Aloe Vera. Alkaline phosphatase, carboxypeptidase, cellulase, lipase and amylase are responsible for the anti-inflammatory property of Aloe vera. On the other hand, anti-oxidant properties are managed by calcium, magnesium, potassium, sodium and zinc minerals. However, they have 12 types of anthraquinones, salicylic acid, β-sisosterol, campesterol, auxin, gibberellin, and essential amino acids for developing medicinal properties among them[1].

Mode of Action

Healing and Anti-inflammatory properties

Glucomannan, Polysaccharides and gibberellin hormone enables to provide the soothing and healing properties. However, these cross-linkages of collagen accelerate the breaking of skin tissues and hyaluronic acids improve healing properties among herb. Mucopolysaccharides’ presence manages the miniaturization of skin and improves wrinkles and soreness.

[1]Razzaq& Mohammed (2019)

Figure 2: working properties of Aloe Vera

(Source: Danish et al. 2020)

Antimicrobial and antiseptic properties

Salicylic acids, nitrogen, phenol and Sulphur compounds inhibit the action of bacteria, fungus and viral infections among skins. Anthraquinones stimulated the immune system of the human body and phorbol myristic acetate prevents cancer cell initiation among the human body[1].

Effects on the immune system

Anthraquinones is vital to increase the intensive water content level among the human body and enhanced the stimulation of muscles. However, calcium influxes manage the stable molecular weight of the body compounds and it activated oxygen free radicals such as neutrophils.

Adverse effect

Taking whole aloe latex orally in one day created major health issues. Excessive in taking of Aloe latex can causes kidney failure and induced several fatal diseases. It can create abdominal cramps and diarrhoea. Therefore, the proper amount of taking is necessary to avoid the adverse effects of Aloe Vera[2].

Case studies

As per the case of acne-related problems among young adult males and women, using Aloe Vera has created a great effect on their problems. 1-35 years of females were facing problems of small inflammation bumps and white heads in check and foreheads. On the other hand, 14 years males have faced skin allergies and irritation. In both cases, aloe Vera gel has been used twice a day. Within three months of using, they got smooth and nourished skin. Therefore, prevention of skin diseases and rashes treatment, Aloe Vera has huge importance[3].

Another case of laboratory experiment of anti-inflammatory property of Aloe Vera in mice shows the treatment in cryptosporidiosis. Using Aloe Vera gel in mice consecutively over 30 days showed the highest parasitic reduction results. It has been managed a 100% reduction of cryptosporidiosis among mice. Aloe Vera helps in developing a better immune system among mice and it manages the Immunosuppressive reasons among the body of the mice[4].

Conclusion

Aloe Vera has several medicinal properties that help in managing several fatal diseases among human beings. On the other hand, the antioxidant properties of Aloe Vera herbs reduce the toxicity level among the human body. It enhances the energy level in daily life and prevents cancerous diseases.

In addition to this excessive intaking of Aloe Vera latex causes severe health issues and diarrhoea. Anti-inflammatory and anti-septic uses of aloe species manage wound healing properties. Curing sunburns, wrinkles and rashes have been prevented by the effective uses of the aloe Vera gel in the body. Eye irritation injuries, lung congestion, arthritis has been managed by the effective nature of Aloe Vera. Daily intaking of Aloe Vera in a particular amount helps in reducing body weight has been very effective. It imposes the immune system of the human being and developed better health. It also helps in managing blood sugar levels among people. Therefore, using medicinal herbs Aloe Vera enhanced development of the society.

[1]Danish et al. (2020)

[2]Leng et al. (2018)

[3]Javed& Shah (2021)

[4]Farid et al. (2021)

References

Nccih (2022), Aloe Vera, Retrieved from: https://www.nccih.nih.gov/health/aloe-vera
Cabi (2022), Aloe vera (true aloe), Retrieved from: https://www.cabi.org/isc/datasheet/4192
Atalayabio (2022), The History of Aloe Vera, Retrieved from: https://tinyurl.com/3zt8tuyb
Azarfam, S. P., Nadian, H., Moezzi, A., &Gholami, A. (2020). Effect of Silicon on Phytochemical and Medicinal Properties of Aloe vera Under Cold Stress. Environmental. Research, 18(1), 561-575, Retrieved from: http://www.aloki.hu/pdf/1801_561575.pdf
Liu, C., Cui, Y., Pi, F., Cheng, Y., Guo, Y., & Qian, H. (2019). Extraction, purification, structural characteristics, biological activities and pharmacological applications of acemannan, a polysaccharide from aloe vera: A review. Molecules, 24(8), 1554, Retrieved from: https://www.mdpi.com/1420-3049/24/8/1554/pdf
Sharma, S., & Sharma, S. (2018). Aloe vera: An ancient herb its components and applications. Journal of Pharmacognosy and Phytochemistry, 7(6), 514-516, retrieved from: https://www.phytojournal.com/archives/2018/vol7issue6/PartI/7-5-602-555.pdf
Razzaq, S. N. A. U., & Mohammed, S. O. (2019). Effect of yeast, kinetin and salicylic acid on the growth of Aloe vera L. plant and on the production of some medicinally active compounds. Plant Archives, 19(1), 511-517, retrieved from: http://www.plantarchives.org/PDF%2019-1/511-517%20(4692A).pdf
Danish, P., Ali, Q., Hafeez, M. M., & Malik, A. (2020). Antifungal and antibacterial activity of aloe vera plant extract. Biological and Clinical Sciences Research Journal, 2020(1), retrieved from: https://bcsrj.com/ojs/index.php/bcsrj/article/download/4/104
Leng, H., Pu, L., Xu, L., Shi, X., Ji, J., & Chen, K. (2018). Effects of aloe polysaccharide, a polysaccharide extracted from Aloe vera, on TNF‑α‑induced HaCaT cell proliferation and the underlying mechanism in psoriasis. Molecular Medicine Reports, 18(3), 3537-3543, Retrieved from: https://www.spandidos-publications.com/10.3892/mmr.2018.9319?text=fulltext
Javed, H., & Shah, S. N. H. (2021). Mild–Moderate Acne TreatmentMild–Moderate Acne Treatment and Skin Allergic Reaction Treatment Using AloeveraEmulgel-A Case Study. RADS Journal of Pharmacy and Pharmaceutical Sciences, 9(2), 148-150, Retrieved from:https://jpps.juw.edu.pk/index.php/jpps/article/download/551/288
Farid, A., Tawfik, A., Elsioufy, B., &Safwat, G. (2021). In vitro and in vivo anti-Cryptosporidium and anti-inflammatory effects of Aloe vera gel in dexamethasone immunosuppressed mice. International Journal for Parasitology: Drugs and Drug Resistance, 17, 156-167, retrieved from: https://www.sciencedirect.com/science/article/pii/S2211320721000452